PedAM

Pediatric Disease Annotations & Medicines


	gingival disease

Disease ID	1035
Disease	gingival disease
Definition	Diseases involving the GINGIVA.
Synonym	disease, gingival diseases, gingival gingiva disorder gingival dis gingival disease (disorder) gingival disease, nos gingival diseases gingival diseases [disease/finding] gingival disorder gingival disorder, nos gum disease gum disease, nos gum disorder gums--diseases parodontosis periodontal disease periodontal diseases
DOID	DOID:1483 DOID:3388
UMLS	C0017563
MeSH	D005882 D010510
SNOMED-CT	SNOMEDCT_US_2016_09_01:18718003
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:104) C0011847 \| diabetes \| 53 C0011860 \| type 2 diabetes \| 14 C0011849 \| diabetes mellitus \| 12 C0042373 \| vascular disease \| 9 C0031099 \| periodontitis \| 9 C0011860 \| type 2 diabetes mellitus \| 9 C0007222 \| cardiovascular disease \| 7 C0017574 \| gingivitis \| 7 C0003864 \| arthritis \| 7 C0948265 \| metabolic syndrome \| 7 C0003873 \| rheumatoid arthritis \| 7 C0018799 \| heart disease \| 6 C0011334 \| caries \| 6 C0004153 \| atherosclerosis \| 6 C0029456 \| osteoporosis \| 5 C0004623 \| bacterial infection \| 4 C0010068 \| coronary heart disease \| 4 C0028754 \| obesity \| 4 C0026636 \| oral disease \| 3 C0013537 \| eclampsia \| 3 C0010068 \| coronary artery disease \| 3 C0017572 \| gingival recession \| 2 C0042373 \| vascular diseases \| 2 C0007222 \| cardiovascular diseases \| 2 C0272187 \| leukocyte adhesion deficiency \| 2 C0004153 \| atherosclerotic vascular disease \| 2 C0022661 \| chronic kidney disease \| 2 C0020456 \| hyperglycemia \| 2 C1704436 \| peripheral arterial disease \| 2 C0022658 \| renal disease \| 2 C0032914 \| preeclampsia \| 2 C0852949 \| arterial disease \| 2 C0042373 \| vascular disorders \| 1 C0003469 \| anxiety disorders \| 1 C0006142 \| breast cancer \| 1 C0037274 \| skin diseases \| 1 C0035851 \| root resorption \| 1 C0409974 \| lupus erythematosus \| 1 C0011854 \| type i diabetes \| 1 C0004096 \| asthma \| 1 C0013473 \| eating disorders \| 1 C0027051 \| myocardial infarction \| 1 C0152021 \| congenital heart disease \| 1 C0271650 \| prediabetes \| 1 C0034065 \| pulmonary embolism \| 1 C0004623 \| bacterial infections \| 1 C0035579 \| rickets \| 1 C0024141 \| systemic lupus erythematosus \| 1 C0030567 \| parkinson's disease \| 1 C0011570 \| depression \| 1 C0042373 \| vascular disorder \| 1 C0733682 \| vitamin d-resistant rickets \| 1 C0011854 \| diabetes mellitus type 1 \| 1 C0003467 \| anxiety \| 1 C0029408 \| osteoarthritis \| 1 C0011334 \| cavities \| 1 C0013338 \| growth hormone deficiency \| 1 C0003469 \| anxiety disorder \| 1 C0022593 \| keratosis \| 1 C0021390 \| inflammatory bowel disease \| 1 C0600260 \| obstructive pulmonary disease \| 1 C0023343 \| leprosy \| 1 C0085207 \| gestational diabetes \| 1 C0037274 \| skin disease \| 1 C0023895 \| liver disease \| 1 C0001080 \| achondroplasia \| 1 C0685938 \| gastrointestinal cancer \| 1 C0024117 \| chronic obstructive pulmonary disease \| 1 C0011854 \| insulin dependent diabetes \| 1 C0010068 \| coronary disease \| 1 C0020538 \| hypertension \| 1 C0038539 \| subdural empyema \| 1 C0040188 \| tic disorders \| 1 C0011854 \| insulin dependent diabetes mellitus \| 1 C0036341 \| schizophrenia \| 1 C0878544 \| cardiomyopathy \| 1 C0031106 \| aggressive periodontitis \| 1 C0017658 \| glomerulonephritis \| 1 C0032460 \| polycystic ovary \| 1 C0024117 \| chronic obstructive pulmonary disease (copd) \| 1 C0162429 \| malnutrition \| 1 C0008924 \| cleft lip \| 1 C0002395 \| alzheimer disease \| 1 C0235974 \| pancreatic cancer \| 1 C0027051 \| myocardial infarct \| 1 C0006840 \| candidiasis \| 1 C0026640 \| oral cancer \| 1 C0022658 \| kidney disease \| 1 C0011854 \| type i diabetes mellitus \| 1 C0013473 \| eating disorder \| 1 C0031069 \| familial mediterranean fever \| 1 C0021831 \| bowel disease \| 1 C0011860 \| type ii diabetes \| 1 C0039103 \| synovitis \| 1 C0010346 \| crohn's disease \| 1 C0024115 \| pulmonary disease \| 1 C0032460 \| polycystic ovary syndrome \| 1 C0007222 \| cardiovascular disorders \| 1 C0038013 \| ankylosing spondylitis \| 1 C0022876 \| preterm labour \| 1 C0003872 \| psoriatic arthritis \| 1 C0011860 \| type ii diabetes mellitus \| 1 C0011854 \| type 1 diabetes \| 1 C0010346 \| crohn disease \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:16) 671 \| BPI \| infer 929 \| CD14 \| infer 1672 \| DEFB1 \| infer 2212 \| FCGR2A \| infer 2215 \| FCGR3B \| infer 3586 \| IL10 \| infer 3552 \| IL1A \| infer 3553 \| IL1B \| infer 3566 \| IL4R \| infer 3569 \| IL6 \| infer 4353 \| MPO \| infer 4846 \| NOS3 \| infer 7097 \| TLR2 \| infer 7099 \| TLR4 \| infer 7124 \| TNF \| infer 3557 \| IL1RN \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:823) 100048912 \| CDKN2B-AS1 \| DISEASES 920 \| CD4 \| DISEASES 1634 \| DCN \| DISEASES 1634 \| DCN \| DISEASES 9341 \| VAMP3 \| DISEASES 7984 \| ARHGEF5 \| DISEASES 83992 \| CTTNBP2 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 3566 \| IL4R \| DISEASES 4804 \| NGFR \| DISEASES 30009 \| TBX21 \| DISEASES 10777 \| ARPP21 \| DISEASES 2191 \| FAP \| DISEASES 22798 \| LAMB4 \| DISEASES 350 \| APOH \| DISEASES 80863 \| PRRT1 \| DISEASES 23411 \| SIRT1 \| DISEASES 266 \| AMELY \| DISEASES 266 \| AMELY \| DISEASES 4616 \| GADD45B \| DISEASES 8216 \| LZTR1 \| DISEASES 5008 \| OSM \| DISEASES 5008 \| OSM \| DISEASES 5594 \| MAPK1 \| DISEASES 3162 \| HMOX1 \| DISEASES 158 \| ADSL \| DISEASES 1511 \| CTSG \| DISEASES 1511 \| CTSG \| DISEASES 3002 \| GZMB \| DISEASES 6655 \| SOS2 \| DISEASES 6655 \| SOS2 \| DISEASES 4792 \| NFKBIA \| DISEASES 55612 \| FERMT1 \| DISEASES 3929 \| LBP \| DISEASES 1472 \| CST4 \| DISEASES 1472 \| CST4 \| DISEASES 51311 \| TLR8 \| DISEASES 7076 \| TIMP1 \| DISEASES 7076 \| TIMP1 \| DISEASES 54 \| ACP5 \| DISEASES 54 \| ACP5 \| DISEASES 4313 \| MMP2 \| DISEASES 4313 \| MMP2 \| DISEASES 79650 \| USB1 \| DISEASES 56942 \| CMC2 \| DISEASES 10423 \| CDIPT \| DISEASES 10404 \| CPQ \| DISEASES 5327 \| PLAT \| DISEASES 5327 \| PLAT \| DISEASES 8797 \| TNFRSF10A \| DISEASES 56729 \| RETN \| DISEASES 7040 \| TGFB1 \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 973 \| CD79A \| DISEASES 3082 \| HGF \| DISEASES 10135 \| NAMPT \| DISEASES 1749 \| DLX5 \| DISEASES 10392 \| NOD1 \| DISEASES 5054 \| SERPINE1 \| DISEASES 5054 \| SERPINE1 \| DISEASES 5919 \| RARRES2 \| DISEASES 5919 \| RARRES2 \| DISEASES 6348 \| CCL3 \| DISEASES 4353 \| MPO \| DISEASES 4353 \| MPO \| DISEASES 1440 \| CSF3 \| DISEASES 8688 \| KRT37 \| DISEASES 6347 \| CCL2 \| DISEASES 6347 \| CCL2 \| DISEASES 6357 \| CCL13 \| DISEASES 1277 \| COL1A1 \| DISEASES 952 \| CD38 \| DISEASES 3381 \| IBSP \| DISEASES 4790 \| NFKB1 \| DISEASES 3558 \| IL2 \| DISEASES 3558 \| IL2 \| DISEASES 116449 \| CLNK \| DISEASES 116449 \| CLNK \| DISEASES 1075 \| CTSC \| DISEASES 1075 \| CTSC \| DISEASES 5829 \| PXN \| DISEASES 969 \| CD69 \| DISEASES 41 \| ASIC1 \| DISEASES 51561 \| IL23A \| DISEASES 3458 \| IFNG \| DISEASES 3458 \| IFNG \| DISEASES 2597 \| GAPDH \| DISEASES 2026 \| ENO2 \| DISEASES 2026 \| ENO2 \| DISEASES 1432 \| MAPK14 \| DISEASES 4015 \| LOX \| DISEASES 4015 \| LOX \| DISEASES 6678 \| SPARC \| DISEASES 7265 \| TTC1 \| DISEASES 3565 \| IL4 \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 4057 \| LTF \| DISEASES 4057 \| LTF \| DISEASES 3273 \| HRG \| DISEASES 3336 \| HSPE1 \| DISEASES 3554 \| IL1R1 \| DISEASES 566 \| AZU1 \| DISEASES 566 \| AZU1 \| DISEASES 5657 \| PRTN3 \| DISEASES 6402 \| SELL \| DISEASES 6402 \| SELL \| DISEASES 1509 \| CTSD \| DISEASES 1509 \| CTSD \| DISEASES 4317 \| MMP8 \| DISEASES 4317 \| MMP8 \| DISEASES 335 \| APOA1 \| DISEASES 1843 \| DUSP1 \| DISEASES 8600 \| TNFSF11 \| DISEASES 8600 \| TNFSF11 \| DISEASES 847 \| CAT \| DISEASES 5552 \| SRGN \| DISEASES 1088 \| CEACAM8 \| DISEASES 54210 \| TREM1 \| DISEASES 718 \| C3 \| DISEASES 6779 \| STATH \| DISEASES 3346 \| HTN1 \| DISEASES 391013 \| PLA2G2C \| DISEASES 22879 \| MON1B \| DISEASES 22879 \| MON1B \| DISEASES 3976 \| LIF \| DISEASES 2658 \| GDF2 \| DISEASES 1315 \| COPB1 \| DISEASES 968 \| CD68 \| DISEASES 968 \| CD68 \| DISEASES 79148 \| MMP28 \| DISEASES 6351 \| CCL4 \| DISEASES 1215 \| CMA1 \| DISEASES 1215 \| CMA1 \| DISEASES 3630 \| INS \| DISEASES 3040 \| HBA2 \| DISEASES 3040 \| HBA2 \| DISEASES 2006 \| ELN \| DISEASES 2006 \| ELN \| DISEASES 348 \| APOE \| DISEASES 55821 \| ALLC \| DISEASES 140683 \| BPIFA2 \| DISEASES 2161 \| F12 \| DISEASES 6382 \| SDC1 \| DISEASES 6382 \| SDC1 \| DISEASES 57050 \| UTP3 \| DISEASES 57050 \| UTP3 \| DISEASES 23135 \| KDM6B \| DISEASES 54453 \| RIN2 \| DISEASES 54453 \| RIN2 \| DISEASES 1401 \| CRP \| DISEASES 1401 \| CRP \| DISEASES 759 \| CA1 \| DISEASES 759 \| CA1 \| DISEASES 4064 \| CD180 \| DISEASES 1828 \| DSG1 \| DISEASES 4907 \| NT5E \| DISEASES 967 \| CD63 \| DISEASES 10220 \| GDF11 \| DISEASES 9392 \| TGFBRAP1 \| DISEASES 3569 \| IL6 \| DISEASES 3569 \| IL6 \| DISEASES 3557 \| IL1RN \| DISEASES 3557 \| IL1RN \| DISEASES 27179 \| IL36A \| DISEASES 27177 \| IL36B \| DISEASES 170680 \| PSORS1C2 \| DISEASES 7097 \| TLR2 \| DISEASES 7097 \| TLR2 \| DISEASES 4316 \| MMP7 \| DISEASES 4316 \| MMP7 \| DISEASES 9313 \| MMP20 \| DISEASES 4322 \| MMP13 \| DISEASES 4322 \| MMP13 \| DISEASES 23314 \| SATB2 \| DISEASES 29081 \| METTL5 \| DISEASES 3685 \| ITGAV \| DISEASES 10060 \| ABCC9 \| DISEASES 11213 \| IRAK3 \| DISEASES 4069 \| LYZ \| DISEASES 4069 \| LYZ \| DISEASES 7450 \| VWF \| DISEASES 3839 \| KPNA3 \| DISEASES 3839 \| KPNA3 \| DISEASES 8120 \| AP3B2 \| DISEASES 999 \| CDH1 \| DISEASES 114294 \| LACTB \| DISEASES 10728 \| PTGES3 \| DISEASES 4092 \| SMAD7 \| DISEASES 4087 \| SMAD2 \| DISEASES 4087 \| SMAD2 \| DISEASES 4025 \| LPO \| DISEASES 4025 \| LPO \| DISEASES 7077 \| TIMP2 \| DISEASES 7077 \| TIMP2 \| DISEASES 10325 \| RRAGB \| DISEASES 25939 \| SAMHD1 \| DISEASES 25939 \| SAMHD1 \| DISEASES 5595 \| MAPK3 \| DISEASES 23523 \| CABIN1 \| DISEASES 23523 \| CABIN1 \| DISEASES 10096 \| ACTR3 \| DISEASES 3552 \| IL1A \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 3553 \| IL1B \| DISEASES 9424 \| KCNK6 \| DISEASES 9424 \| KCNK6 \| DISEASES 1991 \| ELANE \| DISEASES 1991 \| ELANE \| DISEASES 6403 \| SELP \| DISEASES 84680 \| ACCS \| DISEASES 4162 \| MCAM \| DISEASES 10382 \| TUBB4A \| DISEASES 10382 \| TUBB4A \| DISEASES 79594 \| MUL1 \| DISEASES 79594 \| MUL1 \| DISEASES 941 \| CD80 \| DISEASES 59067 \| IL21 \| DISEASES 2247 \| FGF2 \| DISEASES 2247 \| FGF2 \| DISEASES 3004 \| GZMM \| DISEASES 3589 \| IL11 \| DISEASES 3589 \| IL11 \| DISEASES 1356 \| CP \| DISEASES 7474 \| WNT5A \| DISEASES 6774 \| STAT3 \| DISEASES 3383 \| ICAM1 \| DISEASES 3383 \| ICAM1 \| DISEASES 80321 \| CEP70 \| DISEASES 3827 \| KNG1 \| DISEASES 1161 \| ERCC8 \| DISEASES 1950 \| EGF \| DISEASES 1950 \| EGF \| DISEASES 9061 \| PAPSS1 \| DISEASES 27074 \| LAMP3 \| DISEASES 6595 \| SMARCA2 \| DISEASES 6595 \| SMARCA2 \| DISEASES 55749 \| CCAR1 \| DISEASES 55749 \| CCAR1 \| DISEASES 7078 \| TIMP3 \| DISEASES 4060 \| LUM \| DISEASES 4060 \| LUM \| DISEASES 2252 \| FGF7 \| DISEASES 2252 \| FGF7 \| DISEASES 3067 \| HDC \| DISEASES 597 \| BCL2A1 \| DISEASES 597 \| BCL2A1 \| DISEASES 5045 \| FURIN \| DISEASES 5045 \| FURIN \| DISEASES 3687 \| ITGAX \| DISEASES 3394 \| IRF8 \| DISEASES 6687 \| SPG7 \| DISEASES 6455 \| SH3GL1 \| DISEASES 207 \| AKT1 \| DISEASES 8915 \| BCL10 \| DISEASES 2212 \| FCGR2A \| DISEASES 1513 \| CTSK \| DISEASES 1513 \| CTSK \| DISEASES 3756 \| KCNH1 \| DISEASES 4726 \| NDUFS6 \| DISEASES 5921 \| RASA1 \| DISEASES 4794 \| NFKBIE \| DISEASES 526 \| ATP6V1B2 \| DISEASES 3934 \| LCN2 \| DISEASES 4851 \| NOTCH1 \| DISEASES 4851 \| NOTCH1 \| DISEASES 133 \| ADM \| DISEASES 133 \| ADM \| DISEASES 7762 \| ZNF215 \| DISEASES 4863 \| NPAT \| DISEASES 22917 \| ZP1 \| DISEASES 128506 \| OCSTAMP \| DISEASES 83706 \| FERMT3 \| DISEASES 4319 \| MMP10 \| DISEASES 4319 \| MMP10 \| DISEASES 3606 \| IL18 \| DISEASES 3606 \| IL18 \| DISEASES 166785 \| MMAA \| DISEASES 5741 \| PTH \| DISEASES 651 \| BMP3 \| DISEASES 925 \| CD8A \| DISEASES 7070 \| THY1 \| DISEASES 7345 \| UCHL1 \| DISEASES 23643 \| LY96 \| DISEASES 760 \| CA2 \| DISEASES 761 \| CA3 \| DISEASES 245972 \| ATP6V0D2 \| DISEASES 1436 \| CSF1R \| DISEASES 5922 \| RASA2 \| DISEASES 123720 \| WHAMM \| DISEASES 10694 \| CCT8 \| DISEASES 163786 \| SASS6 \| DISEASES 163786 \| SASS6 \| DISEASES 7079 \| TIMP4 \| DISEASES 146433 \| IL34 \| DISEASES 146433 \| IL34 \| DISEASES 5739 \| PTGIR \| DISEASES 9442 \| MED27 \| DISEASES 9442 \| MED27 \| DISEASES 729230 \| CCR2 \| DISEASES 1234 \| CCR5 \| DISEASES 5731 \| PTGER1 \| DISEASES 6352 \| CCL5 \| DISEASES 6352 \| CCL5 \| DISEASES 6368 \| CCL23 \| DISEASES 121214 \| SDR9C7 \| DISEASES 58191 \| CXCL16 \| DISEASES 81570 \| CLPB \| DISEASES 7412 \| VCAM1 \| DISEASES 2215 \| FCGR3B \| DISEASES 3577 \| CXCR1 \| DISEASES 64320 \| RNF25 \| DISEASES 152185 \| SPICE1 \| DISEASES 213 \| ALB \| DISEASES 213 \| ALB \| DISEASES 2921 \| CXCL3 \| DISEASES 6374 \| CXCL5 \| DISEASES 1230 \| CCR1 \| DISEASES 308 \| ANXA5 \| DISEASES 3600 \| IL15 \| DISEASES 3673 \| ITGA2 \| DISEASES 10085 \| EDIL3 \| DISEASES 2150 \| F2RL1 \| DISEASES 1437 \| CSF2 \| DISEASES 4982 \| TNFRSF11B \| DISEASES 4982 \| TNFRSF11B \| DISEASES 1672 \| DEFB1 \| DISEASES 1672 \| DEFB1 \| DISEASES 81501 \| DCSTAMP \| DISEASES 84889 \| SLC7A3 \| DISEASES 63876 \| PKNOX2 \| DISEASES 64112 \| MOAP1 \| DISEASES 161742 \| SPRED1 \| DISEASES 161742 \| SPRED1 \| DISEASES 5055 \| SERPINB2 \| DISEASES 5055 \| SERPINB2 \| DISEASES 144568 \| A2ML1 \| DISEASES 4314 \| MMP3 \| DISEASES 4314 \| MMP3 \| DISEASES 6778 \| STAT6 \| DISEASES 64127 \| NOD2 \| DISEASES 56547 \| MMP26 \| DISEASES 762 \| CA4 \| DISEASES 342574 \| KRT27 \| DISEASES 50964 \| SOST \| DISEASES 23087 \| TRIM35 \| DISEASES 84168 \| ANTXR1 \| DISEASES 116285 \| ACSM1 \| DISEASES 6356 \| CCL11 \| DISEASES 10879 \| SMR3B \| DISEASES 3479 \| IGF1 \| DISEASES 2357 \| FPR1 \| DISEASES 2990 \| GUSB \| DISEASES 2990 \| GUSB \| DISEASES 121340 \| SP7 \| DISEASES 5734 \| PTGER4 \| DISEASES 3308 \| HSPA4 \| DISEASES 140738 \| TMEM37 \| DISEASES 140738 \| TMEM37 \| DISEASES 3689 \| ITGB2 \| DISEASES 3688 \| ITGB1 \| DISEASES 1673 \| DEFB4A \| DISEASES 1673 \| DEFB4A \| DISEASES 126295 \| ZNF57 \| DISEASES 1493 \| CTLA4 \| DISEASES 23246 \| BOP1 \| DISEASES 171558 \| PTCRA \| DISEASES 3596 \| IL13 \| DISEASES 150468 \| CKAP2L \| DISEASES 8403 \| SOX14 \| DISEASES 3627 \| CXCL10 \| DISEASES 118429 \| ANTXR2 \| DISEASES 118429 \| ANTXR2 \| DISEASES 2353 \| FOS \| DISEASES 23261 \| CAMTA1 \| DISEASES 6373 \| CXCL11 \| DISEASES 1470 \| CST2 \| DISEASES 54205 \| CYCS \| DISEASES 27087 \| B3GAT1 \| DISEASES 948 \| CD36 \| DISEASES 948 \| CD36 \| DISEASES 4323 \| MMP14 \| DISEASES 4323 \| MMP14 \| DISEASES 24146 \| CLDN15 \| DISEASES 5340 \| PLG \| DISEASES 5340 \| PLG \| DISEASES 1444 \| CSHL1 \| DISEASES 5222 \| PGA5 \| DISEASES 763 \| CA5A \| DISEASES 3265 \| HRAS \| DISEASES 947 \| CD34 \| DISEASES 947 \| CD34 \| DISEASES 3849 \| KRT2 \| DISEASES 836 \| CASP3 \| DISEASES 7368 \| UGT8 \| DISEASES 1240 \| CMKLR1 \| DISEASES 5319 \| PLA2G1B \| DISEASES 3952 \| LEP \| DISEASES 92745 \| SLC38A5 \| DISEASES 258 \| AMBN \| DISEASES 258 \| AMBN \| DISEASES 713 \| C1QB \| DISEASES 767 \| CA8 \| DISEASES 767 \| CA8 \| DISEASES 931 \| MS4A1 \| DISEASES 931 \| MS4A1 \| DISEASES 1191 \| CLU \| DISEASES 30835 \| CD209 \| DISEASES 3936 \| LCP1 \| DISEASES 260436 \| FDCSP \| DISEASES 4684 \| NCAM1 \| DISEASES 4684 \| NCAM1 \| DISEASES 1068 \| CETN1 \| DISEASES 3579 \| CXCR2 \| DISEASES 80381 \| CD276 \| DISEASES 9370 \| ADIPOQ \| DISEASES 140596 \| DEFB104A \| DISEASES 23765 \| IL17RA \| DISEASES 414325 \| DEFB103A \| DISEASES 414325 \| DEFB103A \| DISEASES 6863 \| TAC1 \| DISEASES 5345 \| SERPINF2 \| DISEASES 5345 \| SERPINF2 \| DISEASES 503618 \| DEFB104B \| DISEASES 3039 \| HBA1 \| DISEASES 3039 \| HBA1 \| DISEASES 4312 \| MMP1 \| DISEASES 4312 \| MMP1 \| DISEASES 10615 \| SPAG5 \| DISEASES 4289 \| MKLN1 \| DISEASES 284273 \| ZADH2 \| DISEASES 284273 \| ZADH2 \| DISEASES 7706 \| TRIM25 \| DISEASES 2 \| A2M \| DISEASES 2 \| A2M \| DISEASES 55894 \| DEFB103B \| DISEASES 55894 \| DEFB103B \| DISEASES 404203 \| SPINK6 \| DISEASES 2200 \| FBN1 \| DISEASES 9622 \| KLK4 \| DISEASES 1237 \| CCR8 \| DISEASES 64327 \| LMBR1 \| DISEASES 4843 \| NOS2 \| DISEASES 22801 \| ITGA11 \| DISEASES 55258 \| THNSL2 \| DISEASES 55258 \| THNSL2 \| DISEASES 633 \| BGN \| DISEASES 633 \| BGN \| DISEASES 1435 \| CSF1 \| DISEASES 4772 \| NFATC1 \| DISEASES 64806 \| IL25 \| DISEASES 64806 \| IL25 \| DISEASES 9241 \| NOG \| DISEASES 1668 \| DEFA3 \| DISEASES 1668 \| DEFA3 \| DISEASES 8905 \| AP1S2 \| DISEASES 10456 \| HAX1 \| DISEASES 10456 \| HAX1 \| DISEASES 50616 \| IL22 \| DISEASES 5121 \| PCP4 \| DISEASES 8651 \| SOCS1 \| DISEASES 286753 \| TUSC5 \| DISEASES 286753 \| TUSC5 \| DISEASES 842 \| CASP9 \| DISEASES 9021 \| SOCS3 \| DISEASES 5155 \| PDGFB \| DISEASES 5155 \| PDGFB \| DISEASES 6401 \| SELE \| DISEASES 6401 \| SELE \| DISEASES 796 \| CALCA \| DISEASES 942 \| CD86 \| DISEASES 4088 \| SMAD3 \| DISEASES 4088 \| SMAD3 \| DISEASES 5104 \| SERPINA5 \| DISEASES 79581 \| SLC52A2 \| DISEASES 682 \| BSG \| DISEASES 682 \| BSG \| DISEASES 3840 \| KPNA4 \| DISEASES 353345 \| GPR141 \| DISEASES 8856 \| NR1I2 \| DISEASES 145447 \| ABHD12B \| DISEASES 114548 \| NLRP3 \| DISEASES 112744 \| IL17F \| DISEASES 64386 \| MMP25 \| DISEASES 64386 \| MMP25 \| DISEASES 7189 \| TRAF6 \| DISEASES 23236 \| PLCB1 \| DISEASES 3572 \| IL6ST \| DISEASES 6002 \| RGS12 \| DISEASES 391 \| RHOG \| DISEASES 3329 \| HSPD1 \| DISEASES 3329 \| HSPD1 \| DISEASES 7100 \| TLR5 \| DISEASES 2358 \| FPR2 \| DISEASES 55552 \| ZNF823 \| DISEASES 401138 \| AMTN \| DISEASES 2804 \| GOLGB1 \| DISEASES 2804 \| GOLGB1 \| DISEASES 81545 \| FBXO38 \| DISEASES 1508 \| CTSB \| DISEASES 1508 \| CTSB \| DISEASES 6590 \| SLPI \| DISEASES 6590 \| SLPI \| DISEASES 145264 \| SERPINA12 \| DISEASES 6633 \| SNRPD2 \| DISEASES 9536 \| PTGES \| DISEASES 921 \| CD5 \| DISEASES 3146 \| HMGB1 \| DISEASES 3716 \| JAK1 \| DISEASES 389400 \| GFRAL \| DISEASES 3605 \| IL17A \| DISEASES 3605 \| IL17A \| DISEASES 1499 \| CTNNB1 \| DISEASES 729967 \| MORN2 \| DISEASES 80142 \| PTGES2 \| DISEASES 25813 \| SAMM50 \| DISEASES 766 \| CA7 \| DISEASES 6146 \| RPL22 \| DISEASES 2879 \| GPX4 \| DISEASES 2879 \| GPX4 \| DISEASES 6275 \| S100A4 \| DISEASES 5154 \| PDGFA \| DISEASES 2326 \| FMO1 \| DISEASES 2331 \| FMOD \| DISEASES 2331 \| FMOD \| DISEASES 79661 \| NEIL1 \| DISEASES 728 \| C5AR1 \| DISEASES 57596 \| BEGAIN \| DISEASES 100506658 \| OCLN \| DISEASES 2204 \| FCAR \| DISEASES 5265 \| SERPINA1 \| DISEASES 5265 \| SERPINA1 \| DISEASES 3240 \| HP \| DISEASES 7068 \| THRB \| DISEASES 344752 \| AADACL2 \| DISEASES 5733 \| PTGER3 \| DISEASES 2224 \| FDPS \| DISEASES 3683 \| ITGAL \| DISEASES 3683 \| ITGAL \| DISEASES 60 \| ACTB \| DISEASES 6597 \| SMARCA4 \| DISEASES 6597 \| SMARCA4 \| DISEASES 871 \| SERPINH1 \| DISEASES 871 \| SERPINH1 \| DISEASES 841 \| CASP8 \| DISEASES 2213 \| FCGR2B \| DISEASES 6364 \| CCL20 \| DISEASES 6364 \| CCL20 \| DISEASES 5294 \| PIK3CG \| DISEASES 81031 \| SLC2A10 \| DISEASES 799 \| CALCR \| DISEASES 126014 \| OSCAR \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 5599 \| MAPK8 \| DISEASES 5599 \| MAPK8 \| DISEASES 1803 \| DPP4 \| DISEASES 54106 \| TLR9 \| DISEASES 9953 \| HS3ST3B1 \| DISEASES 219972 \| MPEG1 \| DISEASES 10319 \| LAMC3 \| DISEASES 6772 \| STAT1 \| DISEASES 10256 \| CNKSR1 \| DISEASES 10256 \| CNKSR1 \| DISEASES 5742 \| PTGS1 \| DISEASES 5742 \| PTGS1 \| DISEASES 7096 \| TLR1 \| DISEASES 7096 \| TLR1 \| DISEASES 7052 \| TGM2 \| DISEASES 7052 \| TGM2 \| DISEASES 54737 \| MPHOSPH8 \| DISEASES 54737 \| MPHOSPH8 \| DISEASES 3775 \| KCNK1 \| DISEASES 2058 \| EPRS \| DISEASES 1378 \| CR1 \| DISEASES 722 \| C4BPA \| DISEASES 9641 \| IKBKE \| DISEASES 7432 \| VIP \| DISEASES 5788 \| PTPRC \| DISEASES 5788 \| PTPRC \| DISEASES 5743 \| PTGS2 \| DISEASES 5743 \| PTGS2 \| DISEASES 356 \| FASLG \| DISEASES 3459 \| IFNGR1 \| DISEASES 2328 \| FMO3 \| DISEASES 6675 \| UAP1 \| DISEASES 26002 \| MOXD1 \| DISEASES 2214 \| FCGR3A \| DISEASES 1490 \| CTGF \| DISEASES 1490 \| CTGF \| DISEASES 9191 \| DEDD \| DISEASES 9191 \| DEDD \| DISEASES 9447 \| AIM2 \| DISEASES 632 \| BGLAP \| DISEASES 632 \| BGLAP \| DISEASES 51175 \| TUBE1 \| DISEASES 92565 \| FANK1 \| DISEASES 6280 \| S100A9 \| DISEASES 6280 \| S100A9 \| DISEASES 4942 \| OAT \| DISEASES 4942 \| OAT \| DISEASES 1520 \| CTSS \| DISEASES 1520 \| CTSS \| DISEASES 639 \| PRDM1 \| DISEASES 6001 \| RGS10 \| DISEASES 5406 \| PNLIP \| DISEASES 914 \| CD2 \| DISEASES 914 \| CD2 \| DISEASES 90025 \| UBE3D \| DISEASES 10768 \| AHCYL1 \| DISEASES 2316 \| FLNA \| DISEASES 3654 \| IRAK1 \| DISEASES 1137 \| CHRNA4 \| DISEASES 959 \| CD40LG \| DISEASES 959 \| CD40LG \| DISEASES 1791 \| DNTT \| DISEASES 3725 \| JUN \| DISEASES 860 \| RUNX2 \| DISEASES 29952 \| DPP7 \| DISEASES 360203 \| GLT6D1 \| DISEASES 7422 \| VEGFA \| DISEASES 7422 \| VEGFA \| DISEASES 958 \| CD40 \| DISEASES 4318 \| MMP9 \| DISEASES 4318 \| MMP9 \| DISEASES 1503 \| CTPS1 \| DISEASES 6385 \| SDC4 \| DISEASES 6385 \| SDC4 \| DISEASES 5328 \| PLAU \| DISEASES 6406 \| SEMG1 \| DISEASES 6406 \| SEMG1 \| DISEASES 60598 \| KCNK15 \| DISEASES 60598 \| KCNK15 \| DISEASES 57158 \| JPH2 \| DISEASES 57158 \| JPH2 \| DISEASES 29889 \| GNL2 \| DISEASES 139322 \| APOOL \| DISEASES 2022 \| ENG \| DISEASES 2833 \| CXCR3 \| DISEASES 4153 \| MBL2 \| DISEASES 22943 \| DKK1 \| DISEASES 7099 \| TLR4 \| DISEASES 7099 \| TLR4 \| DISEASES 9968 \| MED12 \| DISEASES 6676 \| SPAG4 \| DISEASES 164091 \| PAQR7 \| DISEASES 8200 \| GDF5 \| DISEASES 8200 \| GDF5 \| DISEASES 240 \| ALOX5 \| DISEASES 2517 \| FUCA1 \| DISEASES 2582 \| GALE \| DISEASES 23732 \| FRRS1L \| DISEASES 367 \| AR \| DISEASES 249 \| ALPL \| DISEASES 119180 \| LYZL2 \| DISEASES 23569 \| PADI4 \| DISEASES 11240 \| PADI2 \| DISEASES 4758 \| NEU1 \| DISEASES 23013 \| SPEN \| DISEASES 23013 \| SPEN \| DISEASES 10673 \| TNFSF13B \| DISEASES 10673 \| TNFSF13B \| DISEASES 4795 \| NFKBIL1 \| DISEASES 50943 \| FOXP3 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 9375 \| TM9SF2 \| DISEASES 80324 \| PUS1 \| DISEASES 6839 \| SUV39H1 \| DISEASES 3105 \| HLA-A \| DISEASES 1471 \| CST3 \| DISEASES 1471 \| CST3 \| DISEASES 765 \| CA6 \| DISEASES 285641 \| SLC36A3 \| DISEASES 7102 \| TSPAN7 \| DISEASES 7102 \| TSPAN7 \| DISEASES 6354 \| CCL7 \| DISEASES 650 \| BMP2 \| DISEASES 9308 \| CD83 \| DISEASES 9308 \| CD83 \| DISEASES 6303 \| SAT1 \| DISEASES 2625 \| GATA3 \| DISEASES 1906 \| EDN1 \| DISEASES 1906 \| EDN1 \| DISEASES 10631 \| POSTN \| DISEASES 10631 \| POSTN \| DISEASES 3456 \| IFNB1 \| DISEASES 10670 \| RRAGA \| DISEASES 265 \| AMELX \| DISEASES 265 \| AMELX \| DISEASES 2813 \| GP2 \| DISEASES 2813 \| GP2 \| DISEASES 90865 \| IL33 \| DISEASES 90865 \| IL33 \| DISEASES 29126 \| CD274 \| DISEASES 55835 \| CENPJ \| DISEASES 51199 \| NIN \| DISEASES 80333 \| KCNIP4 \| DISEASES 752014 \| CEMP1 \| DISEASES 1667 \| DEFA1 \| DISEASES 728358 \| DEFA1B \| DISEASES 3083 \| HGFAC \| DISEASES 440163 \| RNASE13 \| DISEASES 10675 \| CSPG5 \| DISEASES 10675 \| CSPG5 \| DISEASES 2878 \| GPX3 \| DISEASES 56953 \| NT5M \| DISEASES 284266 \| SIGLEC15 \| DISEASES 9208 \| LRRFIP1 \| DISEASES 9208 \| LRRFIP1 \| DISEASES 54499 \| TMCO1 \| DISEASES 2113 \| ETS1 \| DISEASES 3886 \| KRT35 \| DISEASES 3886 \| KRT35 \| DISEASES 64115 \| C10orf54 \| DISEASES 64115 \| C10orf54 \| DISEASES 6696 \| SPP1 \| DISEASES 2919 \| CXCL1 \| DISEASES 6387 \| CXCL12 \| DISEASES 655 \| BMP7 \| DISEASES 10117 \| ENAM \| DISEASES 10117 \| ENAM \| DISEASES 54959 \| ODAM \| DISEASES 114884 \| OSBPL10 \| DISEASES 4780 \| NFE2L2 \| DISEASES 9425 \| CDYL \| DISEASES 9425 \| CDYL \| DISEASES 5609 \| MAP2K7 \| DISEASES 594857 \| NPS \| DISEASES 729857 \| RGPD2 \| DISEASES 54826 \| GIN1 \| DISEASES 54826 \| GIN1 \| DISEASES 150365 \| MEI1 \| DISEASES 6654 \| SOS1 \| DISEASES 6654 \| SOS1 \| DISEASES 7018 \| TF \| DISEASES 554226 \| ANKRD30BL \| DISEASES 7852 \| CXCR4 \| DISEASES 57703 \| CWC22 \| DISEASES 1385 \| CREB1 \| DISEASES 10941 \| UGT2A1 \| DISEASES 7009 \| TMBIM6 \| DISEASES 23210 \| JMJD6 \| DISEASES 23210 \| JMJD6 \| DISEASES 3550 \| IK \| DISEASES 10725 \| NFAT5 \| DISEASES 960 \| CD44 \| DISEASES 7124 \| TNF \| DISEASES 7124 \| TNF \| DISEASES 3491 \| CYR61 \| DISEASES 7072 \| TIA1 \| DISEASES 4615 \| MYD88 \| DISEASES 4049 \| LTA \| DISEASES 6892 \| TAPBP \| DISEASES 388372 \| CCL4L1 \| DISEASES 2821 \| GPI \| DISEASES 2821 \| GPI \| DISEASES 9498 \| SLC4A8 \| DISEASES 139728 \| PNCK \| DISEASES 81704 \| DOCK8 \| DISEASES 3612 \| IMPA1 \| DISEASES 3612 \| IMPA1 \| DISEASES 6349 \| CCL3L1 \| DISEASES 55655 \| NLRP2 \| DISEASES 55655 \| NLRP2 \| DISEASES 834 \| CASP1 \| DISEASES 448835 \| LCE6A \| DISEASES 3586 \| IL10 \| DISEASES 3586 \| IL10 \| DISEASES 629 \| CFB \| DISEASES 55799 \| CACNA2D3 \| DISEASES 26137 \| ZBTB20 \| DISEASES 5478 \| PPIA \| DISEASES 5478 \| PPIA \| DISEASES 127933 \| UHMK1 \| DISEASES 6949 \| TCOF1 \| DISEASES 2638 \| GC \| DISEASES 51428 \| DDX41 \| DISEASES 80745 \| THUMPD2 \| DISEASES 80745 \| THUMPD2 \| DISEASES 100289462 \| DEFB4B \| DISEASES 2920 \| CXCL2 \| DISEASES 253970 \| SFTA3 \| DISEASES 4168 \| MCF2 \| DISEASES 4168 \| MCF2 \| DISEASES 727897 \| MUC5B \| DISEASES 930 \| CD19 \| DISEASES 930 \| CD19 \| DISEASES 9414 \| TJP2 \| DISEASES 441864 \| TARM1 \| DISEASES 441864 \| TARM1 \| DISEASES 1232 \| CCR3 \| DISEASES 3684 \| ITGAM \| DISEASES 3684 \| ITGAM \| DISEASES 8725 \| URI1 \| DISEASES 8725 \| URI1 \| DISEASES 7421 \| VDR \| DISEASES 8972 \| MGAM \| DISEASES 8742 \| TNFSF12 \| DISEASES 8778 \| SIGLEC5 \| DISEASES 728276 \| CLEC19A \| DISEASES 820 \| CAMP \| DISEASES 820 \| CAMP \| DISEASES 1506 \| CTRL \| DISEASES 8792 \| TNFRSF11A \| DISEASES 54757 \| FAM20A \| DISEASES 54757 \| FAM20A \| DISEASES 8740 \| TNFSF14 \| DISEASES 246734 \| NPCDR1 \| DISEASES 246734 \| NPCDR1 \| DISEASES 6689 \| SPIB \| DISEASES 6689 \| SPIB \| DISEASES 11012 \| KLK11 \| DISEASES 100302740 \| FAS-AS1 \| DISEASES 3262 \| HPVC1 \| DISEASES 55539 \| KCNQ1DN \| DISEASES 55539 \| KCNQ1DN \| DISEASES 100506495 \| LIFR-AS1 \| DISEASES 79104 \| MEG8 \| DISEASES 100873918 \| MME-AS1 \| DISEASES 7955 \| RNF217-AS1 \| DISEASES 26766 \| RNU105C \| DISEASES 23642 \| SNHG1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1035
Disease	gingival disease
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:66) HP:0000819 \| Diabetes mellitus \| 12 HP:0000230 \| Inflamed gums \| 9 HP:0000704 \| Pyorrhea \| 9 HP:0001369 \| Arthritis \| 7 HP:0001370 \| Rheumatoid arthritis \| 7 HP:0000670 \| Dental caries \| 6 HP:0012531 \| Pain \| 6 HP:0006480 \| Premature loss of teeth \| 6 HP:0002621 \| Atherosclerosis \| 6 HP:0000939 \| Osteoporosis \| 5 HP:0001513 \| Obesity \| 4 HP:0001677 \| Coronary artery disease \| 4 HP:0100601 \| Eclampsia \| 3 HP:0001518 \| Small for gestational age \| 3 HP:0001297 \| Cerebral vascular events \| 3 HP:0003074 \| High blood glucose \| 2 HP:0100812 \| bad breath \| 2 HP:0012622 \| Chronic kidney disease \| 2 HP:0000217 \| Dry mouth syndrome \| 2 HP:0002140 \| Ischemic stroke \| 2 HP:0000166 \| Severe periodontal disease \| 2 HP:0010885 \| Aseptic necrosis \| 2 HP:0004950 \| Peripheral artery disease \| 2 HP:0006349 \| Agenesis of permanent dentition \| 2 HP:0000855 \| Insulin resistance \| 2 HP:0030816 \| Gum recession \| 2 HP:0100602 \| Pre-eclampsia \| 2 HP:0005978 \| Noninsulin dependent diabetes mellitus \| 1 HP:0002748 \| Rickets \| 1 HP:0002758 \| Osteoarthritis \| 1 HP:0100769 \| Synovitis \| 1 HP:0001907 \| Thromboembolic disease \| 1 HP:0000824 \| Growth hormone deficiency \| 1 HP:0000739 \| Anxiety \| 1 HP:0000147 \| Sclerocystic ovaries \| 1 HP:0010783 \| Erythema \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0012592 \| Albuminuria \| 1 HP:0000099 \| Glomerular nephritis \| 1 HP:0100785 \| Insomnia \| 1 HP:0009800 \| gestational diabetes \| 1 HP:0001249 \| Mental retardation \| 1 HP:0001638 \| Cardiomyopathy \| 1 HP:0001945 \| Fever \| 1 HP:0002099 \| Asthma \| 1 HP:0002894 \| Neoplasia of the pancreas \| 1 HP:0002511 \| Late-onset form of familial Alzheimer disease \| 1 HP:0000716 \| Depression \| 1 HP:0006510 \| Chronic obstructive pulmonary disease \| 1 HP:0003077 \| Hyperlipidemia \| 1 HP:0002204 \| Pulmonary embolism \| 1 HP:0100753 \| Schizophrenia \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0001622 \| Premature delivery \| 1 HP:0100651 \| Type I diabetes mellitus \| 1 HP:0000822 \| Hypertension \| 1 HP:0100033 \| Tic disorder \| 1 HP:0100280 \| Morbus Crohn \| 1 HP:0005202 \| Helicobacter pylori infection \| 1 HP:0000790 \| Hematuria \| 1 HP:0003002 \| Breast carcinoma \| 1 HP:0002719 \| infections, recurrent \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0002797 \| Increased bone resorption \| 1 HP:0004395 \| Malnutrition \| 1 HP:0002721 \| Immunodeficiency \| 1

Disease ID	1035
Disease	gingival disease
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:19) C0080233 \| tooth loss \| 26 C0426768 \| o sign \| 14 C0009450 \| infection \| 10 C0011389 \| dental plaque \| 7 C0002382 \| alveolar bone loss \| 6 C0029456 \| osteoporosis \| 5 C0399451 \| subgingival plaque \| 5 C0004623 \| bacterial infection \| 4 C0038454 \| stroke \| 3 C0162644 \| root caries \| 3 C0275524 \| polymicrobial infection \| 2 C0018520 \| halitosis \| 2 C0238790 \| bone destruction \| 2 C0035851 \| root resorption \| 1 C0011570 \| depression \| 1 C0004610 \| bacteraemia \| 1 C0029166 \| oral manifestations \| 1 C0011854 \| type i diabetes mellitus \| 1 C0034065 \| pulmonary emboli \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:27)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1143634	24460370	3553	IL1B	umls:C0017563	BeFree	We investigated associations between three IL1 single-nucleotide polymorphisms (SNPs) in genes encoding interleukin (IL) -1α (rs1800587) and IL-1β (rs1143634 and rs16944) and the risk of periodontal disease among young Japanese women.	0.010314791	2014	IL1B	2	112832813	G	A
rs1143634	24460370	3553	IL1B	umls:C0031090	BeFree	We investigated associations between three IL1 single-nucleotide polymorphisms (SNPs) in genes encoding interleukin (IL) -1α (rs1800587) and IL-1β (rs1143634 and rs16944) and the risk of periodontal disease among young Japanese women.	0.029251047	2014	IL1B	2	112832813	G	A
rs16944	24460370	3553	IL1B	umls:C0017563	BeFree	We investigated associations between three IL1 single-nucleotide polymorphisms (SNPs) in genes encoding interleukin (IL) -1α (rs1800587) and IL-1β (rs1143634 and rs16944) and the risk of periodontal disease among young Japanese women.	0.010314791	2014	IL1B	2	112837290	A	G
rs16944	24460370	3553	IL1B	umls:C0031090	BeFree	We investigated associations between three IL1 single-nucleotide polymorphisms (SNPs) in genes encoding interleukin (IL) -1α (rs1800587) and IL-1β (rs1143634 and rs16944) and the risk of periodontal disease among young Japanese women.	0.029251047	2014	IL1B	2	112837290	A	G
rs1799983	16881803	4846	NOS3	umls:C0017563	BeFree	Endothelial nitric oxide synthase Glu298Asp gene polymorphism in periodontal diseases.	0.000271442	2006	NOS3	7	150999023	T	G
rs1799983	16881803	4846	NOS3	umls:C0031090	BeFree	Endothelial nitric oxide synthase Glu298Asp gene polymorphism in periodontal diseases.	0.002638474	2006	NOS3	7	150999023	T	G
rs1800587	24460370	3553	IL1B	umls:C0031090	BeFree	We investigated associations between three IL1 single-nucleotide polymorphisms (SNPs) in genes encoding interleukin (IL) -1α (rs1800587) and IL-1β (rs1143634 and rs16944) and the risk of periodontal disease among young Japanese women.	0.029251047	2014	IL1A	2	112785383	G	C,A
rs1800587	24460370	3553	IL1B	umls:C0017563	BeFree	We investigated associations between three IL1 single-nucleotide polymorphisms (SNPs) in genes encoding interleukin (IL) -1α (rs1800587) and IL-1β (rs1143634 and rs16944) and the risk of periodontal disease among young Japanese women.	0.010314791	2014	IL1A	2	112785383	G	C,A
rs2275913	23137879	3605	IL17A	umls:C0031090	BeFree	Our data suggest that IL17A and the presence of IL17A (rs2275913) A allele are associated with the absence of periodontal disease.	0.086263026	2013	IL17A	6	52186235	G	A
rs2275913	23137879	3605	IL17A	umls:C0017563	BeFree	Our data suggest that IL17A and the presence of IL17A (rs2275913) A allele are associated with the absence of periodontal disease.	0.000814326	2013	IL17A	6	52186235	G	A
rs4358188	16893388	671	BPI	umls:C0031090	BeFree	A645G (Lys216Glu) polymorphism of the bactericidal/permeability-increasing protein gene in periodontal disease.	0.005362824	2006	BPI;LOC105372612	20	38318446	G	A
rs4986790	17309585	4695	NDUFA2	umls:C0031090	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.001357209	2007	TLR4	9	117713024	A	G
rs4986790	17309585	929	CD14	umls:C0017563	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.001357209	2007	TLR4	9	117713024	A	G
rs4986790	17309585	7099	TLR4	umls:C0017563	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.001357209	2007	TLR4	9	117713024	A	G
rs4986790	17309585	4695	NDUFA2	umls:C0017563	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.001357209	2007	TLR4	9	117713024	A	G
rs4986790	17309585	7099	TLR4	umls:C0031090	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.006091273	2007	TLR4	9	117713024	A	G
rs4986790	23879541	7099	TLR4	umls:C0031090	BeFree	Therefore, the aim of this study was to investigate the association between the TLR4 Asp299Gly and Thr399Ile polymorphism and periodontal disease.	0.006091273	2014	TLR4	9	117713024	A	G
rs4986790	23879541	7099	TLR4	umls:C0017563	BeFree	Therefore, the aim of this study was to investigate the association between the TLR4 Asp299Gly and Thr399Ile polymorphism and periodontal disease.	0.001357209	2014	TLR4	9	117713024	A	G
rs4986790	17309585	929	CD14	umls:C0031090	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.013907006	2007	TLR4	9	117713024	A	G
rs4986791	17309585	929	CD14	umls:C0031090	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.013907006	2007	TLR4	9	117713324	C	T
rs4986791	23879541	7099	TLR4	umls:C0017563	BeFree	Therefore, the aim of this study was to investigate the association between the TLR4 Asp299Gly and Thr399Ile polymorphism and periodontal disease.	0.001357209	2014	TLR4	9	117713324	C	T
rs4986791	17309585	4695	NDUFA2	umls:C0031090	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.001357209	2007	TLR4	9	117713324	C	T
rs4986791	23879541	7099	TLR4	umls:C0031090	BeFree	Therefore, the aim of this study was to investigate the association between the TLR4 Asp299Gly and Thr399Ile polymorphism and periodontal disease.	0.006091273	2014	TLR4	9	117713324	C	T
rs4986791	17309585	929	CD14	umls:C0017563	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.001357209	2007	TLR4	9	117713324	C	T
rs4986791	17309585	7099	TLR4	umls:C0017563	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.001357209	2007	TLR4	9	117713324	C	T
rs4986791	17309585	7099	TLR4	umls:C0031090	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.006091273	2007	TLR4	9	117713324	C	T
rs4986791	17309585	4695	NDUFA2	umls:C0017563	BeFree	Genotyping for the TLR4 single-nucleotide polymorphisms (SNPs) Asp299Gly, Thr399Ile and the CD14 SNPs -159 and -1359 was completed for subjects with periodontal disease compared with control subjects.	0.001357209	2007	TLR4	9	117713324	C	T

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0017563	fluoxetine	D005473	54910-89-3	periodontal diseases	MESH:D010510	therapeutic	21966942
C0017563	nicotine	D009538	-	periodontal diseases	MESH:D010510	marker/mechanism	12200972
C0017563	nitric oxide	D009569	10102-43-9	periodontal diseases	MESH:D010510	marker/mechanism	24040572

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)